Which of the following statement(s) regarding gated channels is/are FALSE? Gated channels facilitate the passage of... (2024)

FAQs

Which of the following statements regarding gated channels is false? ›

Final answer: Statement 3 asserting that gated channels are always open is false because gated channels can open or close in response to different stimuli.

Final answer: A gated channel responds to specific stimuli and will remain closed if unstimulated. The stimuli that trigger opening can vary, such as chemical signals or physical distortions, and after activation, these channels can become temporarily inactivated.

The plasma membrane of all electrically excitable cells—not only neurons, but also muscle, endocrine, and egg cells—contains voltage-gated cation channels, which are responsible for generating the action potentials.

Answer and Explanation: The only true statement about voltage-gated ion channels is that a. they open in response to change in the membrane potential.

Typical examples of neurotransmitter-gated ion channels are the acetylcholine receptor in neuromuscular junctions and the Glu, Gly, and GABA receptors in the central nervous system. These receptors are multimeric proteins.

What are Gated ion channels? Pores in the membrane that open and close in a regulated manner. Allows the passage of ions. Tap the card to flip 👆

Gated channel proteins are structurally and functionally different from non-gated proteins. They play a critical role in several cellular functions. Gated channel proteins remain closed at all times, which allows electrical energy to build up inside the cell.

Three functional components of the channel are required: a permeation pathway (pore), gates that permit or deny the movement of ions through the pore, and a voltage sensor that changes its conformation in response to changes of membrane potential.

Voltage-gated sodium ion channels can exist in three main conformational states: closed, open, and inactivated. They change from one conformational state to the other on neurotransmitter binding.

In contrast to APs, graded potentials are smaller voltage potentials which vary in their voltage between 1 and 50 mV (hence called 'graded' potentials). They are generated by the interplay of ligand-gated channels which are located chiefly in the membranes of dendrites and a few in the somata (Figs 2.4 & 2.5).

What type of gated channel is most likely be activated by neurotransmitters? ›

Many types of ion channels respond to chemical signals (ligands) rather than to changes in the membrane potential (Figure 4.4E-G). The most important of these ligand-gated ion channels in the nervous system is the class activated by binding neurotransmitters (Figure 4.4E).

Active channels, or gates, are either opened or closed in response to an external electrical or chemical stimulation. The active channels are also selective and allow only specific ions to pass through the membrane.

Expert-Verified Answer. Ion channels are proteins that form a channel in the cell membrane and allow ions to flow down their concentration gradient. The statement voltage-gated ion channels only open when a stimulus is applied is true.

Voltage-gated ion channels are multisubunit protein complexes that respond to changes in membrane potential with conformational changes that lead to gating, or opening and closing, of an ion-selective transmembrane pore.

Voltage-gated ion channels are multisubunit protein complexes that respond to changes in membrane potential with conformational changes that lead to gating, or opening and closing, of an ion-selective transmembrane pore.

3) Each channel lets both positive and negative ions flow through the pore. This statement is generally true. Gated ion channels can be selective in the ions they allow to pass through, some channels are non-selective and allow both positive and negative ions to flow through the pore.

A key feature of potassium channel function is the ability to switch between conducting and non-conducting states by undergoing conformational changes in response to cellular or extracellular signals. Such switching is facilitated by the mechanical coupling of gating domain movements to pore opening and closing.

Gated channel proteins are structurally and functionally different from non-gated proteins. They play a critical role in several cellular functions. Gated channel proteins remain closed at all times, which allows electrical energy to build up inside the cell.

Channels may be gated by membrane potential, ligand binding, mechanical stress, or intracellular second messengers such as Ca²⁺ or cyclic nucleotides (cAMP and cGMP). In a quiescent cell, the membrane potential is hyperpolarized to −65 mV and most of the voltage-gated channels are in a closed, resting state.